Aciclovir (Acyclovir) for Herpes & Shingles Treatment | Uses, Dosage & Side Effects
Learn how Aciclovir (Acyclovir / Zovirax) treats herpes, cold sores, shingles, and chickenpox. Updated 2025 guide on dosage, side effects, precautions, and safe usage.
Effectiveness of Aciclovir (Acyclovir / Zovirax) in Treating Herpes and Skin Viral Infections
Aciclovir (also spelled Acyclovir) is an antiviral medication commonly prescribed for infections caused by the Herpes Simplex Virus (HSV) and the Varicella-Zoster Virus (VZV).
These viruses cause conditions such as:
- Genital Herpes
- Cold Sores (Oral Herpes)
- Shingles (Herpes Zoster)
- Chickenpox (Varicella)
Aciclovir is available as oral tablets, capsules, suspension, topical cream, and ointment.
The form your doctor prescribes depends on the severity and location of the infection:
| Condition | Common Form Used |
| Mild cold sores / oral herpes | Aciclovir cream / ointment |
| Genital herpes | Tablets or ointment |
| Shingles | Higher-dose tablets |
| Chickenpox | Tablets (in adults / older children) |
How It Works:
Aciclovir does not cure herpes, but it reduces viral replication, shortens outbreaks, decreases pain, and helps symptoms heal faster. It also reduces the frequency of recurrent outbreaks when taken as suppressive therapy.
Before Using Aciclovir – Important Considerations
Inform your doctor if any of the following apply:
- Pregnancy or breastfeeding
- Kidney problems or dehydration
- Weakened immune system
- Allergies to antiviral medicines
- Currently taking other prescription or herbal medicines
How to Take Aciclovir (Dosage Guidelines)
Typical dosage varies depending on diagnosis:
| Condition | Standard Adult Dosage | Duration |
| Shingles | 800 mg 5 times daily | 7–10 days |
| Initial Genital Herpes Outbreak | 200 mg 5 times daily | 7–10 days |
| Recurrent Herpes Outbreak | 200 mg 5 times daily | 5 days |
| Herpes Suppression (Daily Prevention) | 400 mg twice daily | 6–12 months |
| Chickenpox (Adults/children >40kg) | 800 mg 4 times daily | 5 days |
Important:
- Space doses evenly throughout the day.
- Drink plenty of water to protect your kidneys.
- Finish the full course, even if symptoms improve earlier.
Using Aciclovir Cream / Ointment
- Apply 5 times daily to affected skin.
- Apply at the first sign of tingling or burning (before blisters form).
- Wash hands before and after application to avoid spreading infection.
Precautions to Prevent Spreading Herpes
- Avoid sexual contact when sores are present.
- Use a condom even when no symptoms are visible (virus can still shed).
- Avoid touching sores, and avoid sharing lip products.
Possible Side Effects of Aciclovir
Common Side Effects (Mild):
- Nausea, vomiting, or diarrhea
- Headache or dizziness
- Tiredness
- Mild skin irritation with cream
Less Common but Serious Side Effects (Seek Immediate Care):
- Confusion or hallucinations
- Severe rash or blistering
- Decreased urination / kidney function problems
- Unusual bleeding or bruising
Older adults and people with kidney disease are more likely to experience side effects.
Storage Instructions
- Store in a cool, dry place away from sunlight.
- Keep out of reach of children.
- Do not use expired medication.
Buying Aciclovir / Acyclovir Online
Aciclovir is available by prescription in most countries. Some over-the-counter cold sore creams contain mild antiviral ingredients.
When purchasing online:
- Choose licensed pharmacies
- Check brand authenticity
- Avoid unverified sellers offering uncontrolled antiviral tablets
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