Acyclovir (Zovirax) Uses, Dosage, Side Effects & Herpes Treatment Guide
Acyclovir (Zovirax) Uses, Dosage, Side Effects & Herpes Treatment Guide
Acyclovir (Zovirax) is an antiviral medication used to treat herpes infections including genital herpes, cold sores, chickenpox, and shingles. Learn dosage, side effects, safety tips, and who should avoid this medication.
Acyclovir (Zovirax): Updated Medical and Consumer Information
Acyclovir, sold under the brand name Zovirax, is an antiviral medication used to treat infections caused by herpes viruses, including:
- Herpes Simplex Virus Type 1 (HSV-1) – causes cold sores
- Herpes Simplex Virus Type 2 (HSV-2) – causes genital herpes
- Varicella-Zoster Virus (VZV) – causes chickenpox and shingles
Acyclovir works by stopping the virus from multiplying, which helps reduce symptoms and speeds healing. It does not cure herpes, because the virus stays inactive in nerve cells and may reactivate later.
Acyclovir is available as:
- Tablets
- Capsules
- Oral Suspension (Liquid)
- Topical Cream/Ointment
- IV Injection (for severe infections in hospitals)
What Is Acyclovir Used For?
| Condition | What It Helps With |
| Genital Herpes | Reduces pain, itching, outbreak duration, and frequency |
| Cold Sores (Fever Blisters) | Speeds healing of oral lesions |
| Shingles (Herpes Zoster) | Reduces nerve pain and rash severity |
| Chickenpox | Helps shorten illness duration, especially in children |
| Prevention in Immunocompromised Patients | Helps prevent serious viral complications |
Acyclovir may also be prescribed to people with weakened immune systems, including those with HIV/AIDS, cancer, or transplant history.
How to Take Acyclovir (Zovirax)
- Take 2 to 5 times daily, depending on condition and prescription.
- Can be taken with or without food.
- Drink plenty of water to protect the kidneys.
- Begin treatment as soon as symptoms appear (tingling, itching, blister).
If Using Liquid Acyclovir
- Shake well before each dose.
- Measure with a medicine measuring spoon, not a household spoon.
Keep the Drug Level Steady
- Take doses at evenly spaced times throughout the day.
Dosage (General Guidance — Exact Dose Depends on Doctor)
| Condition | Typical Adult Dose |
| Genital Herpes (first episode) | 400 mg 3 times daily for 7–10 days |
| Recurrent Herpes Outbreak | 400 mg 3 times daily for 5 days |
| Shingles | 800 mg 5 times daily for 7–10 days |
| Cold Sores | 400 mg 5 times daily for 5 days |
| Chickenpox (Children) | Dose based on body weight (doctor determines) |
Do not change your dose without your doctor’s approval.
Missed Dose
- Take it when remembered.
- If it’s almost time for the next dose, skip the missed dose.
- Do not double dose.
Overdose Warning
Too much acyclovir can cause kidney damage.
Symptoms of overdose may include:
- Confusion or agitation
- Extreme drowsiness
- Seizures
- Decreased urine output
Seek emergency medical help if these occur.
Possible Side Effects
Common:
- Nausea / Vomiting
- Diarrhea
- Headache
- Dizziness
- Fatigue
Less Common:
- Hair thinning
- Swelling (fluid retention)
- Joint or muscle pain
Serious (Seek medical help):
- Confusion or hallucinations
- Reduced urination or kidney pain
- Rash or allergic reaction
Precautions and Safety Information
Tell your doctor if you have:
- Kidney disease
- Dehydration
- Weak immune system (HIV/AIDS, cancer therapy)
- Are pregnant or breastfeeding
Older adults and people with kidney issues may need lower doses.
Alcohol and marijuana can increase dizziness, so use caution.
Important Notes
- Acyclovir does NOT prevent transmission of genital herpes.
- Use condoms/dental dams and avoid sexual contact during outbreaks.
- You can still spread herpes even without visible sores.
Storage
- Store at room temperature (15°C–25°C / 59°F–77°F).
- Keep away from moisture and heat.
- Keep out of reach of children.
- Do not flush down the toilet; dispose properly when expired.
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