What Is Alobar Holoprosencephaly?
Alobar Holoprosencephaly Alobar holoprosencephaly is a subtype of holoprosencephaly (HPE), and is the most severe of the classical three subtypes, with both semilobar and lobar holoprosencephaly having less severe clinical manifestations. Holoprosencephaly is a congenital Induction disorder of the brain occurring at 3-6 weeks’ gestation, with failed segmentation of the neural tube. This leads to […]