Accessory Atrioventricular Pathways: Causes, Diagnosis, and Modern Ablation Treatments
Accessory Atrioventricular Pathways: Causes, Diagnosis, and Modern Ablation Treatments Understanding Accessory Atrioventricular Pathways and Preexcitation Arrhythmias Introduction Accessory atrioventricular (AV) pathways are abnormal muscular connections that allow electrical impulses to travel directly between the atria and ventricles, bypassing the normal AV node-His-Purkinje conduction system. This results in ventricular preexcitation, often seen in Wolff-Parkinson-White (WPW) syndrome, […]
What Is Agammaglobulinemia?
Agammaglobulinemia Agammaglobulinemia, or hypogammaglobulinemia, is the most common of the primary immunodeficiencies, accounting for approximately 50% of cases. Three major types can be described: X-linked, early onset, and late onset. After more than 50 years since the clinical entity was first described by Bruton in 1952, the molecular defect in X-linked agammaglobulinemia (XLA) has been […]
What Is Congenital Afibrinogenemia?
Congenital Afibrinogenemia Congenital afibrinogenemia is a rare, genetically inherited blood fibrinogen disorder in which the blood does not clot normally due to the lack of fibrinogen, a blood protein necessary for coagulation. Congenital afibrinogenemia is a bleeding disorder caused by impairment of the blood clotting process. Normally, blood clots protect the body after an injury […]
What Is Alpha-1 Antitrypsin Deficiency?
Alpha-1 Alpha-1 antitrypsin deficiency is an inherited disorder that may cause lung disease and liver disease. The signs and symptoms of the condition and the age at which they appear vary among individuals. People with alpha-1 antitrypsin deficiency usually develop the first signs and symptoms of lung disease between ages 20 and 50. The earliest […]
What Is Alpha High-Density Lipoprotein Deficiency(Tangier Disease)?
Alpha High-Density Lipoprotein Deficiency(Tangier Disease) Tangier disease (also known as Familial alpha-lipoprotein deficiency) or hypoalphalipoproteinemia is a rare inherited disorder characterized by a severe reduction in the amount of high density lipoprotein (HDL), often referred to as “good cholesterol”, in the bloodstream. Tangier disease is an inherited disorder characterized by significantly reduced levels of high-density […]
What Is Alpers Disease?
Alpers Disease Alpers disease is a progressive, neurodevelopmental, mitochondrial DNA depletion syndrome characterized by three co-occurring clinical symptoms: psychomotor regression (dementia); seizures; and liver disease. It is an autosomal recessive disease caused by mutation in the gene for the mitochondrial DNA polymerase POLG. The disease occurs in about one in 100,000 persons. Most individuals with […]
What is Alopecia Cicatrisata (Pseudopelade)?
Alopecia Cicatrisata (Pseudopelade) Pseudopelade is also known as Alopecia Cicatrisata. Pseudopelade is a very rare condition primarily affecting women and sometimes children. Initially, Pseudopelade causes development of well-defined patches of hair loss which for some people may deteriorate to near total scalp hair loss with individual surviving hairs. The history of Pseudopelade for affected individuals […]
What Is ACC? (Aplasia Cutis Congenita)
ACC (Aplasia Cutis Congenita) Aplasia cutis congenita (ACC) is a heterogenous group of disorders characterized by the absence of a portion of skin in a localized or widespread area at birth. First reported by Cordon in 1767, aplasia cutis congenita manifests as a solitary defect on the scalp in 70% of cases, but it may […]
What Is Alopecia Celsi?
Alopecia Celsi Alopecia areata is a disorder characterized by loss of hair. Sometimes, this means simply a few bare patches on the scalp. In other cases, hair loss is more extensive. Although the exact cause is not known, this is thought to be an autoimmune disorder in which the immune system, the body’s own defense […]
Acanthotic Nevus (Seborrheic Keratosis): Causes, Symptoms, Diagnosis & Treatment
Acanthotic Nevus (Seborrheic Keratosis): Causes, Symptoms, Diagnosis & Treatment Learn about acanthotic nevus, also known as seborrheic keratosis. Understand causes, symptoms, histology, risk factors, diagnosis, treatment methods, and how to differentiate from melanoma. Acanthotic Nevus (Seborrheic Keratosis): Overview Acanthotic nevus is a clinical synonym historically used to describe seborrheic keratosis, a benign (non-cancerous) skin growth. […]
What Is Septic Arthritis? Symptoms, Diagnosis and Treatment
What Is Septic Arthritis Overview Septic arthritis is also known as infectious arthritis, and is usually caused by bacteria. It can also be caused by a virus or fungus. The condition is an inflammation of a joint that’s caused by infection. Typically, septic arthritis affects one large joint in the body, such as the knee or hip. Less frequently, […]
What Is Froelich’s Syndrome?
Froelich’s Syndrome? It is possible that the main title of the report Froelich’s Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms of Froelich’s Syndrome Adiposogenital Dystrophy Babinski-Froelich Syndrome Dystrophia Adiposogenitalis Frolich’s Syndrome Hypothalamic Infantilism-Obesity Launois-Cleret Syndrome Sexual Infantilism General Discussion Froehlich syndrome is a […]